Naivex (Dolotegravir) is an FDA-approved medicine. It is used for the treatment and therapeutic approach of HIV infection. Naivex is an integrase inhibitor. By integrating blockade, HIV integrase inhibitors prevent their multiplication and can reduce the amount of HIV in the body.
Mechanism of action:
Naivex (Dolotegravir) is an HIV-1 antiviral agent. It inhibits HIV integration by binding to the active site and thus blocks the transferring step in the integration of retroviral DNA. This is an essential step in the HIV replication cycle and will result in inhibition of viral activity.
Posology and method of administration:
Take Naivex (Dolotegravir) exactly as a health care provider tells you. Naive or experienced treatment with INSTI-naive: 50 mg once a day.
50mg twice a day. INSTITUES experience with certain substitutions associated with INSTI resistance or clinical suspected INSTI
50mg twice a day. Caution: Concomitant administration of dofetilide due to increased potency of dofetilide plasma concentrations and the risk of serious and / or life-threatening events.